The AI Museum
AI Analytics1,072 recordsRecounted 23 September 2026

Open-weight biology models in 2022

9

Models

8 organisations

100%

Open weights

9 open, 0 closed

0

Frontier

By Epoch's flag

25B

Largest traceable

GenSLM

2022

Span

7 with a traceable size

Releases

by month
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sept
Oct
Nov
Dec

Records

9
Open-weight biology models in 2022, newest first. Each row links to the source Epoch AI records for it.
ModelOrganisationReleasedParametersWeights
DiffDockMassachusetts Institute of Technology (MIT)2022-1020M *Open
GenSLMUniversity of Chicago2022-1025BOpen
ESM2-15BMeta AI2022-0715BOpen
ProGen2-xlargeSalesforce Research2022-066BOpen
TranceptionUniversity of Oxford2022-05700MOpen
BERT-RBPWaseda University2022-04110MOpen
ProteinBERTHebrew University of Jerusalem2022-0216MOpen
AbLang (heavy sequences)University of Oxford2022-01355MOpen
OntoProteinZhejiang University (ZJU)2022-01420M *Open

An asterisk marks a parameter figure the source does not consider traceable to the people who built the model. That judgement is the source’s and it has false negatives: Kimi K3 is marked speculative at 2.8T while Moonshot’s own model card states the figure. Why that distinction carries the whole exhibit.

Counts are of models Epoch AI records as notable, not of every model released. The most recent month is always incomplete, because a model enters the dataset when it is reviewed rather than when it ships.

Epoch AI, 'Data on AI Models'. Published online at epoch.ai. Retrieved from 'https://epoch.ai/data/ai-models-documentation' Used under CC BY 4.0.

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